Diabetic Nephropathy

Can we restore GBM function in DN?

What are the regulators of glomerular basement membranes? Can we target glomerular endothelium and podocytes to restore normal barrier components and functions?

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Diabetic Nephropathy

What next after RAAS blockade?

At the current time, we only have RAAS blockade and hypertension control to slow progression to ESRD. What mechanisms should be targeted to slow progression (loss of GFR) in diabetic nephropathy?

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